Dr. Norbert Jost Name: Dr. Norbert Jost

Addresses: Information
Telephone: 36-62-54 6885, 54 6111
Telefax: 36-62-545-680
skype: jost_norbert
E-mail: jost.norbert@med.u-szeged.hu


Positions: associate professor

Educational background:
-1990-1995. University of Szeged, Faculty of Physics, Szeged, Hungary
-1995-1999. Postgraduate training at the Albert Szent-Györgyi Medical University, Szeged
-2000. PhD degree obtained at the University of Szeged, Albert Szent-Györgyi Medical and Pharmaceutical Center (Title of the PhD thesis: Pharmacological modulation of the rapid and slow components of the delayed rectifier potassium current in mammalian cardiac cells.)
-2009 University Habilitation in theoretical medicine

Fellowships:
-2002-2004, Marie Curie EU Fellowship (Department of Pharmacology, TU Dresden, Germany, supervisor Profs E. Wettwer and U. Ravens

Memberships:
- Hungarian Society of Cardiology (1996)
- International Society for Heart Research (ISHR, 1996)
- European Working Group on Cardiac Cellular Electrophysiology (EWGCCE, 1996)
- European Society for Cardiology (1997)
- Hungarian Society for Experimental and Clinical Pharmacology (2001)

Research interest: cardiac cellular electrophysiology and pharmacology, patch-clamp technique on isolated mammalian cardiac cells

  Experience:
- Structure and function of the transmembrane currents in the cardiac ventricular and atrial action potential in physiological and pathophysiological conditions
- In vitro study of the effects different investigational drugs (OR-10103, tedisamil, dronedarone, GYKI-16638, AWD compounds, SEA-0400, GLG-V13, etc.) on several transmembrane currents in isolated mammalian myocytes.

Awards:
- II. prize; (of the National Students` Scientific Council Award (OTDK), physics section, 1995)
- I. prize (Young Investigators Award of the Hungarian Society of Cardiology, Balatonfüred, 1998)
- I. prize and Dr. Cserháti Medallion (Dr. Cserháti Young Investigators Award of the Albert Szent-Györgyi Medical University Szeged, 1998)
- III. prize (Young Investigators Award of the Hungarian Society of Cardiology, Balatonfüred, 2000)
- Young Investigator Research Award (Dr. György Gábor Foundation's Award, 2001)
- Bolyai János Research Fellowship (Hungarian Academy of Sciences, 2002, 2005, 2008)
-Sanofi-Aventis prize (2007)

Publication records:
44 per reviewed full length papers (in English)
3 book editing
8 book chapters
> 90
published abstracts (in English)
Cumulative impact factor:
155.926
Cited references (without self citations): 1281
Full researcher profile: Researcher profile:  http://www.researchgate.net/profile/Norbert_Jost/ )

List of publications:

Muntean DM, Kiss L, Jost N, Baczkó I: ATP-sensitive potassium channel modulators and cardiac arrhythmias: an update, Current Pharmaceutical Design, 21(8), 1091-1102, 2015
Impact factor: 3.288
Number of independent citations: 1

Jost N, Nagy N, Kohajda Z, Horváth A, Corici C, Acsai K, Biliczki P, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Toth A, Papp JGy, Varró A, Virág L: ORM-10103, a novel specific inhibitor of the sodium/calcium exchanger, decreases early and delayed afterdepolarization in the canine heart., British Journal of Pharmacology, epub, doi: 10.1111/bph.12228, 2013
Impact factor: 4.990
Number of independent citations: 3

Jost N, Virág L, Comtois P, Ördög B, Szűts V, Seprényi Gy, Bitay M, Kohajda Zs, Koncz I, Nagy N, Szél T, Magyar J, Kovács M, Puskás LG, Lengyel Cs, Wettwer E, Ravens U, Nanasi PP, Papp JGy, Varró A, Nattel S: Ionic mechanisms limiting cardiac repolarization-reserve in humans compared to dogs, Journal of Physiology, 591 (17), 4189–4206, 2013
Impact factor: 4.544
Number of independent citations: 5

N Jost, Zs. Kohajda, A. Kristóf, P. P. Kovács, Z. Husti, V. Juhász, L. Kiss, A. Varró, L. Virág, I. Baczkó: Atrial remodelling and novel pharmacological strategies for antiarrhythmic therapy in atrial fibrillation (review)., Current Medicinal Chemistry, 18, 3675-3694, 2011
Impact factor: 4.859
Number of independent citations: 6

N. Jost, K. Acsai, B. Horváth, T. Bányász, I. Baczkó, M. Bitay, G. Bogáts, P.P. Nánási: Contribution of IKr and IK1 to ventricular repolarization in canine and human myocytes. Is there any influence of action potential duration, Basic Research in Cardiology, 104, 33-41, 2009
Impact factor: 5.973
Number of independent citations: 9

D. Dobrev, A. Friedrich, N. Voigt, N. Jost, E. Wettwer, T. Christ, M. Knaut, U. Ravens: The G-protein gated potassium current IK,ACh is constitutively active in patients with chronic atrial fibrillation., Circulation, 112: 3697 - 3706, 2005
Impact factor: 11.632
Number of independent citations: 182

N. Jost, L. Virág, M. Bitay, J. Takács, Cs. Lengyel, P. Biliczki, Z.A. Nagy, G. Bogáts, D.A.Lathrop, J. Gy. Papp, A. Varró: Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle, Circulation, 112: 1392-1399, 2005
Impact factor: 11.632
Number of independent citations: 170

N. Jost, L. Virág, O. Hála, A. Varró, D. Thormählen, J. Gy. Papp: Effect of the antifibrillatory compound tedisamil (KC-8857) on transmembrane currents in mammalian ventricular myocytes, Current Medicinal Chemistry, 11, 3219-3228, 2004
Impact factor: 4.382
Number of independent citations: 12

A. Varró, B. Baláti, N. Iost, J. Takács, L. Virág, D. A. Lathrop, C. Lengyel, L. Tálosi, J. Gy. Papp: The role of the delayed rectifier component IKs in dog ventricular muscle and Purkinje fibre repolarization, Journal of Physiology (London), 523, 67-81, 2000
Impact factor: 4.455
Number of independent citations: 141

Iost N, Virag L, Opincariu M, Szecsi J, Varro A, Papp JGy: Delayed rectifier potassium current in undiseased human ventricular myocytes, CARDIOVASC RES 40: (3) 508-515, 1998
Impact factor: 2.996
Number of independent citations: 55

Last update: February, 2015

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