Nagy Norbert Name: Dr. Norbert Nagy PhD

Research Associates

Addresses: Information
Telephone: 36-62-542-453
Telefax: 36-62-545-680

E-mail: nagynorbert1@gmail.com


Educational background:
1997-2001 Horváth Mihály High School, Szentes
2001-2006
University of Szeged, Faculty of Science and Informatics
2006-2012
PhD degree obtained at Department of Pharmacology and Pharmacotherapy University of Szeged. Title of the thesis:
                  “Calcium-dependent modulation of  the cardiac repolarization”
2012-         
Research fellow at MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary.

Memberships:
- International Society of Heart Research
- European Working Group on Cardiac Cellular Electrophysiology (EWGCCE, 2007)
- Hungarian Society of Cardiology (2008)
- Hungarian Society of Pharmacology (2016)

Field of research
Cardiac cellular electrophysiology and pharmacology; cardiac Na+-Ca2+ homeostasis

Awards
Travel Grant for EWGCCE, 2011, Oslo, Norway
Postdoctoral Programme of the Hungarian Academy of Sciences 2013-2015, 2015-2017
First prize in poster competition, IACS, Balatongyörök, Hungary, 2014
First prize in poster competition, IACS, Omaha (NB), USA, 2015

Language
-English intermediate
-Spanish intermediate

Selected  publications

Acsai K, Kun A, Farkas AS, Fülöp F, Nagy N, Balázs M, Szentandrássy N, Nánási PP, Papp JG, Varró A., Tóth A.
Effect of partial blockade of the Na(+)/Ca(2+)-exchanger on Ca(2+) handling in isolated rat ventricular myocytes.
Eur J Pharmacol. 2007 Dec 8;576(1-3):1-6. Epub 2007 Jul 31.

Birinyi P, Tóth A, Jóna I, Acsai K, Almássy J, Nagy N, Prorok J, Gherasim I, Papp Z, Hertelendi Z, Szentandrássy N, Bányász T, Fülöp F, Papp JG, Varró A, Nánási PP, Magyar J.
The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2+ transient and contractility in canine ventricular cardiomyocytes.
Cardiovasc Res. 2008 Jun 1;78(3):476-84. Epub 2008 Feb 5.

Farkas AS, Acsai K, Nagy N, Tóth A, Fülöp F, Seprényi G, Birinyi P, Nánási PP, Forster T, Csanády M, Papp JG, Varró A, Farkas A.
Na(+)/Ca(2+) exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart.
Br J Pharmacol. 2008 May;154(1):93-104. Epub 2008 Mar 10. Erratum in: Br J Pharmacol. 2008 May;154(1):256-7.

Nagy N, Szuts V, Horváth Z, Seprényi G, Farkas AS, Acsai K, Prorok J, Bitay M, Kun A, Pataricza J, Papp JG, Nánási PP, Varró A, Tóth A.
Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
J Mol Cell Cardiol. 2009 Nov;47(5):656-63. Epub 2009 Jul 24.

Jost N, Nagy N, Corici C, Kohajda Zs, Horváth A, Acsai K, Biliczki P, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Tóth A, Papp JGy, Varró A, Virág L
ORM-10103, a novel specific inhibitor of the sodium/calcium exchanger, decreases early and delayed afterdepolarization in the canine heart.
British J. of Pharmacol. (2013)

Nagy N, Acsai K, Kormos A, Sebők Z, Farkas AS, Jost N, Nánási PP, Papp JG, Varró A, Tóth A.
[Ca²⁺] i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium.
Pflugers Arch. 2013 Nov;465(11):1621-35. doi: 10.1007/s00424-013-1309-x. Epub 2013 Jun 27.

Jost N, Virág L, Comtois P, Ordög B, Szuts V, Seprényi G, Bitay M, Kohajda Z, Koncz I, Nagy N, Szél T, Magyar J, Kovács M, Puskás LG, Lengyel C, Wettwer E, Ravens U, Nánási PP, Papp JG, Varró A, Nattel S.
Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs.
J Physiol. 2013 Sep 1;591(Pt 17):4189-206. doi: 10.1113/jphysiol.2013.261198. Epub 2013 Jul 22.

Kormos A, Nagy N, Acsai K, Váczi K, Ágoston S, Pollesello P, Levijoki J, Szentandrássy N, Papp JG, Varró A, Tóth A.
Efficacy of selective NCX inhibition by ORM-10103 during simulated ischemia/reperfusion.
Eur J Pharmacol. 2014 Oct 5;740:539-51. doi: 10.1016/j.ejphar.2014.06.033. Epub 2014 Jun 27.

Nagy N, Kormos A, Kohajda Z, Szebeni Á, Szepesi J, Pollesello P, Levijoki J, Acsai K, Virág L, Nánási PP, Papp JG, Varró A, Tóth A.
Selective Na(+) /Ca(2+) exchanger inhibition prevents Ca(2+) overload-induced triggered arrhythmias.
Br J Pharmacol. 2014 Dec;171(24):5665-81. doi: 10.1111/bph.12867.

Norbert Nagy, Tamás Szél, Norbert Jost, András Tóth, Julius Gy. Papp, András Varró
Novel experimental results in human cardiac electrophysiology: measurement of the Purkinje fibre action potential from the undiseased human heart
Canadian J. of Phys. (2015)

Kohajda Z, Farkas-Morvay N, Jost N, Nagy N, Geramipour A, Horváth A, Varga RS, Hornyik T, Corici C, Acsai K, Horváth B, Prorok J, Ördög B, Déri S, Tóth D, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Tóth A, Baczkó I, Leprán I, Nánási PP, Papp JG, Varró A, Virág L.
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments.
PLoS One. 2016 Nov

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