Dr. Végh Ágnes Név / name: Dr. Végh Ágnes
Position: Professor of Pharmacology
Tel.: +36-62-545-673
E-mail: vegh@phcol.szote.u-szeged.hu

Date of birth: 1954, Nova, Hungary

Education:  1960-1968 Primary school, Szolnok
                    1968-1972 Middle school: Verseghy Ferenc Gimnázium, Szolnok
                    1972-1977 Attila József University, Faculty of Natural Sciences, Biology
                    1974-1977 Students of Scientific Circle at the Department of
                    Comparative Physiology

Qualification: 1977 Attila József University, Szeged, Faculty of Natural
                        Sciences, Degree in biology "Summa cum laude"

Postgradual studies:
        1977-1981 Albert Szent-Györgyi Medical University, Department
                            of Pharmacodynamy
        1981 University Doctor Degree (`Doctor Biologiae Medicinalis)
                        "Summa cum laude"

Scientific degrees:
        1987 Candidate of Medical Sciences (later Ph.D.1998)
        1999 Doctor of Science (D.Sc.)

Scientific awords:
        1983 First prize in a competition of young scientists conducted
                by the Hungarian Cardiological Society
        1997-2001 Széchenyi Professorship

University career and previous positions:
        1977-1981 Albert Szent-Györgyi Medical University, Department of Pharmacodynamy
                            Position: Scientific coworker
        1977-1982 Albert Szent-Györgyi Medical University, Department of Pharmacology
                            Position: Scientific coworker
        1983-1987 Albert Szent-Györgyi Medical University, Department of Pharmacology
                            Position: Lecturer
        1987-1995 Albert Szent-Györgyi Medical University, Department of Pharmacology
                            Position: Senior lecturer
        1992- Visiting Honorary Research Fellow, at the Department of Physiology & Pharmacology,University of Strathclyde,
Glasgow
        1995-1999 Albert Szent-Györgyi Medical University, Department of Pharmacology
                            Position: Associate Professor
        1999 Albert Szent-Gyöegyi Medical University   Habilitation: Title: Med. Habil.
        1999 Albert Szent-Györgyi Medical University, Department of Pharmacology
                            Position: Full Professor

Research interest: Cardiovascular physiology, pathophysiology and pharmacology; experimental models of myocardial ischaemia and infarction, cardiac arrhythmias, coronary circulation, modelling of heart failure, testing of newly developed antiischaemic and antiarrhythmic compounds, adaptation mechanisms in the heart during myocardial ischaemia.

Teaching experience: Pharmacology (lectures and seminars) from 1981 up to present to undergraduate students
Cardiovascular Pharmacology - postgraduate level (from 1987 -)

Published Papers: Thesis: 3
Full papers: 81 (English)
Book chapters: 17 (English)
Published abstracts: over100 (English)
Membership of Societies:
    1981- Hungarian Pharmacological Society
            (Council member from 1995 up to present) 1982- Hungarian Physiological Society
            (Council member from 1999 up to present)
    1981- Hungarian Cardiological Society
    1981- International Society for Heart Research
            (Council member from 1998 up to present)
    1993- British Pharmacological Society
    1996- Fellow of the European Society of Cardiology
    1996- The British Society for Cardiovascular Research
    1997- Working Group on Cellular Biology of the Heart
    2000- International Society of Cardiovascular Pharmacotherapy

Grants: Hungarian National Scientific Research Foundation
            OTKA: project leader (1991-1994; 1994-1997;1998-2001; 1999-2002)
            The Wellcome Trust (1991-1994) travel and research fund
            EEC grant "Network for Cardioprotection" (BMHI-CT-92-1893, ERC-CIPA-CT094-4009)
            Joint Grant of the British Council and the Hungarian
            Technological Research Development (OMFB)
            OMFB-British Council: hungarian project leader (1993-1996)
            Joint Grant of the British Council and the Hungarian
            Ministry of Culture and Education (MKM)
            MKM-British Council hungarian project leader (1996-1999)
            MKM (1996-1997) project leader
            FKFP (1997-2001) project leader
            ETT (1997-1999; 2000-2002) project leader

Other activities:   Editor: British Journal of Pharmacology (1997-2001)
                            Referee: Cardiovascular Research
                                British Journal of Pharmacology
                                Journal of Molecular Cell Biochemistry
                                Brain Research Bulletin
                                Life Sciences
                                Biochemical Pharmacology
                                Journal of Experimental and Clinical Cardiology
                            Member: Health Care Scientific Committee (1997-)
                            Symposium organiser at Scientific Meetings (e.g.
                            International Society for Heart Research, World Congress,
                            Greece, 1998; European Pharmacological Society
                            Meeting, Budapest, 1999)
                Organiser of the 22nd European Section Meeting of ISHR,
                July 3 to 6, 2002, Szeged, Hungary


 

Ten most important publications:

Végh Á., Szekeres L., Udvary É.: Effect of blood supply to the normal noninfarcted myocardium on the incidence and severity of early postocclusion arrhythmias in dogs. Basic Res Cardiol, 82: 159-171, 1987.

Végh Á., Szekeres L., Parratt J.R.: Protective effects of preconditioning of the ischaemic myocardium involve cyclo-oxygenase products. Cardiovasc Res, 24: 1020-1023, 1990.

Végh Á., Szekeres L., Parratt J.R.: Transient ischaemia induced by rapid cardiac pacing results in myocardial preconditioning. Cardiovasc Res, 25: 1051-1053, 1991.

Végh Á., Komori S., Szekeres L., Parratt J.R.: Antiarrhythmic effects of preconditioning in anaesthetized dogs and rats. Cardiovasc Res, 26: 487-495, 1992.

Végh Á., Szekeres L., Parratt J.R.: Preconditioning of the ischaemic myocardium; involvement of the L-arginine - nitric oxide pathway. Br J Pharmacol, 107: 648-652, 1992.

Végh Á., Papp J.Gy., Parratt J.R.: Prevention by dexamethasone of the marked antiarrhythmic effects of preconditioning induced 20 h after rapid cardiac pacing. Br J Pharmacol, 113: 1081-1082, 1994.

Kaszala K, Végh Á., Papp J.Gy., Parratt J.R.: Time course of the protection against ischaemia and reperfusion induced ventricular arrhythmias resulting from brief periods of cardiac pacing. J Mol Cell Cardiol, 28: 2085-2095, 1996.

Parratt J.R., Végh Á.: Delayed protection against ventricular arrhythmias by cardiac pacing. Heart (editorial), 78: 423-425, 1997.

Kis A., Végh Á., Papp J.Gy., Parratt J.R.: Repeated cardiac pacing extends the time during which canine hearts are protected against ischaemia-induced arrhythmias. Role of nitric oxide. J Mol Cell Cardiol, 31: 1229-1241, 1999.

Babai L., Szigeti Zs., Parratt J.R., Végh Á.: Delayed cardioprotective effects of exercise in dogs are aminoguanidine sensitive: possible involvement of nitric oxide. Clin Sci; 102: , 2002.